Friday, June 29, 2012

Tixylix Chesty Cough





1. Name Of The Medicinal Product



Tixylix® Chesty Cough


2. Qualitative And Quantitative Composition



Each 5ml contains Guaifenesin 50mg



For excipients see section 6.1



3. Pharmaceutical Form



Linctus



A clear, colourless or straw coloured solution



4. Clinical Particulars



4.1 Therapeutic Indications



Expectorant for the symptomatic relief of acute productive (chesty) cough.



The linctus is for the lubrication and relief of the sore throat and hoarseness, which may be associated with the cough.



4.2 Posology And Method Of Administration



The following dose is taken 4 hourly. Do not exceed 6 doses in 24 hours.



Tixylix Chesty Cough is contra-indicated in children under 6 years of age.



6 – 10 years 5 to 10ml



Not to be used for more than 5 days without the advice of a doctor. Parents or carers should seek medical advice if the child's condition deteriorates during treatment.



Do not exceed the stated dose.



Keep out of the sight and reach of children.



4.3 Contraindications



Hypersensitivity to the active ingredients or to any of the excipients.



Not to be used in children under 6 years of age.



4.4 Special Warnings And Precautions For Use



Consult a doctor before use if suffering from an acute asthma attack, a chronic cough or are asthmatic.



Stop use and consult a healthcare professional if the cough persists for longer than 5 days.



Stop use and consult a healthcare professional if the cough is accompanied by a fever, rash or persistent headache or is recurrent.



If symptoms persist, consult a doctor.



Keep out of the sight and reach of children.



Do not exceed the stated dose.



Do not take with any other cough and cold medicine, including cough suppressants.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



Should not be taken with a cough suppressant.



If urine is collected within 24 hours of a dose of Tixylix Chesty Cough a metabolite of guaifenesin may cause a colour interference with laboratory determinations of urinary 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid (VMA).



4.6 Pregnancy And Lactation



No special warnings or precautions.



4.7 Effects On Ability To Drive And Use Machines



None.



4.8 Undesirable Effects



The following side effects may be associated with the use of guaifenesin:



Gastro-intestinal Disorders: nausea, vomiting



Immune System Disorders: hypersensitivity reactions



4.9 Overdose



Symptoms of very large overdosage are nausea and vomiting. Guaifenesin is, however, rapidly metabolised and excreted in the urine. Patients should be kept under observation and treated symptomatically.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Guaifenesin is reported to reduce the viscosity of tenacious sputum and is used as an expectorant.



5.2 Pharmacokinetic Properties



Guaifenesin is readily absorbed from the gastrointestinal tract. It is readily metabolised and excreted in the urine. It has a plasma half life of 1 hour.



5.3 Preclinical Safety Data



None.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Sodium benzoate



Sodium saccharin



Glycerol



Sorbital solution (70%) (Non-cryst)



Citric acid monohydrate or anhydrous citric acid



Blackcurrant flavour DA13624



Vanilla flavour NN21166



Acesulfame Potassium



Hydroxyethylcellulose



Purified water



6.2 Incompatibilities



None.



6.3 Shelf Life



36 months.



6.4 Special Precautions For Storage



Store below 25ºC.



6.5 Nature And Contents Of Container



Container: Amber glass bottles



Closure: Wadded, aluminium roll-on pilfer-proof closure (ROPP)



or



Wadded, polypropylene or polypropylene/HDPE child resistant tamper evident closure



Wad: PVdC-coated. Board or EPE



Each bottle contains 100 ml.



6.6 Special Precautions For Disposal And Other Handling



Keep all medicines out of the reach of children.



7. Marketing Authorisation Holder



Novartis Consumer Health UK Limited



Wimblehurst Road



Horsham



West Sussex



RH12 5AB



Trading as Novartis Consumer Health



8. Marketing Authorisation Number(S)



PL 00030/0082



9. Date Of First Authorisation/Renewal Of The Authorisation



Granted: 1 August 1997



10. Date Of Revision Of The Text



04 June 2009



Legal category: P




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chlorpheniramine, hydrocodone, and phenylephrine


Generic Name: chlorpheniramine, hydrocodone, and phenylephrine (KLOR fe NEER a meen, HYE droe KOE done, FEN il EFF rin)

Brand names: B-Tuss, Coughtuss, Cytuss HC, De-Chlor HC, DroTuss-CP, Ed-TLC, Ed-Tuss HC, Endal-HD Plus, H-C Tussive, Histussin-HC, Hydro-PC II, Hydro-PC II Plus, Hydron CP, Liquicough HC, Maxi-Tuss HCX, Mintuss MS, Neo HC, Poly-Tussin, Poly-Tussin HD, Relacon-HC, Relacon-HC NR, Relasin-HC, Rindal HD Plus, Rindal-HD, Triant-HC, Tusana-D, Z-Cof HC, ...show all 73 brand names.


What is chlorpheniramine, hydrocodone, and phenylephrine?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.


Hydrocodone is a narcotic cough medicine.


Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


The combination of chlorpheniramine, hydrocodone, and phenylephrine is used to treat runny or stuffy nose, sinus congestion, and cough caused by the common cold or flu.


Chlorpheniramine, hydrocodone, and phenylephrine may also be used for purposes not listed in this medication guide.


What is the most important information I should know about chlorpheniramine, hydrocodone, and phenylephrine?


Do not take this medication if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use chlorpheniramine, hydrocodone, and phenylephrine before the MAO inhibitor has cleared from your body. Chlorpheniramine, hydrocodone, and phenylephrine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine, hydrocodone, and phenylephrine. Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by chlorpheniramine, hydrocodone, and phenylephrine. Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Never share hydrocodone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

What should I discuss with my healthcare provider before taking chlorpheniramine, hydrocodone, and phenylephrine?


Do not take this medication if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. Serious, life threatening side effects can occur if you use chlorpheniramine, hydrocodone, and phenylephrine before the MAO inhibitor has cleared from your body. You should not use chlorpheniramine, hydrocodone, and phenylephrine if you are allergic to it.

To make sure you can safely take this medication, tell your doctor if you have any of these other conditions:



  • asthma, COPD, sleep apnea, or other breathing disorder;



  • liver or kidney disease;


  • heart disease or high blood pressure;




  • diabetes;




  • a thyroid disorder;




  • curvature of the spine;




  • a history of head injury or brain tumor;




  • epilepsy or other seizure disorder;




  • low blood pressure;




  • glaucoma;




  • gallbladder disease;




  • Addison's disease or other adrenal gland disorders;




  • enlarged prostate, urination problems;




  • mental illness; or




  • a history of drug or alcohol addiction.




Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Never share hydrocodone with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. FDA pregnancy category C. It is not known whether chlorpheniramine, hydrocodone, and phenylephrine will harm an unborn baby. Hydrocodone may cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using chlorpheniramine, hydrocodone, and phenylephrine. It is not known whether chlorpheniramine, hydrocodone, and phenylephrine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take chlorpheniramine, hydrocodone, and phenylephrine?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


You may take this medication with or without food.


Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Hydrocodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

See also: Chlorpheniramine, hydrocodone, and phenylephrine dosage (in more detail)

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of hydrocodone can be fatal.

Overdose symptoms may include extreme drowsiness, feeling restless or nervous, vomiting, stomach pain, warmth or tingly feeling, seizure (convulsions), pinpoint pupils, confusion, cold and clammy skin, weak pulse, shallow breathing, fainting, or breathing that stops.


What should I avoid while taking chlorpheniramine, hydrocodone, and phenylephrine?


Chlorpheniramine, hydrocodone, and phenylephrine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of chlorpheniramine, hydrocodone, and phenylephrine.

Chlorpheniramine, hydrocodone, and phenylephrine side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • severe dizziness, anxiety, restless feeling, or nervousness;




  • fast, pounding, or uneven heartbeats;




  • shallow breathing, slow heartbeat;




  • confusion, hallucinations, unusual thoughts or behavior;




  • feeling like you might pass out;




  • urinating less than usual or not at all;




  • easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms;




  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, chest pain, shortness of breath, seizure); or




  • upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).



Less serious side effects may include:



  • nausea, vomiting, upset stomach, constipation;




  • dry mouth;




  • blurred vision;




  • dizziness, drowsiness;




  • problems with memory or concentration;




  • sleep problems (insomnia);




  • ringing in your ears;




  • warmth, tingling, or redness under your skin; or




  • skin rash or itching.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Chlorpheniramine, hydrocodone, and phenylephrine Dosing Information


Usual Adult Dose for Cough and Nasal Congestion:

Chlorpheniramine/hydrocodone/phenylephrine 2 mg-6 mg-12 mg/5 mL oral liquid:
5 to 10 mL orally every 4 to 6 hours not to exceed 50 mL daily.

Chlorpheniramine/hydrocodone/phenylephrine 2.5 mg-3.5 mg-8 mg/5 mL oral liquid:
Chlorpheniramine/hydrocodone/phenylephrine 2.5 mg-3.25 mg-8 mg/5 mL oral liquid:
10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/hydrocodone/phenylephrine 3 mg-5 mg-7.5 mg/5 mL oral liquid:
5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/hydrocodone/phenylephrine 2 mg-2.5 mg-10 mg/5 mL oral liquid:
10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Usual Pediatric Dose for Cough and Nasal Congestion:

Chlorpheniramine/hydrocodone/phenylephrine 2 mg-6 mg-12 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 to 6 hours not to exceed 25 mL daily
12 yrs or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 50 mL daily.

Chlorpheniramine/hydrocodone/phenylephrine 2.5 mg-3.5 mg-8 mg/5 mL oral liquid:
Chlorpheniramine/hydrocodone/phenylephrine 2.5 mg-3.25 mg-8 mg/5 mL oral liquid:
Chlorpheniramine/hydrocodone/phenylephrine 2 mg-2.5 mg-10 mg/5 mL oral liquid:
6 to 11 yrs: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily
12 yrs or older: 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/hydrocodone/phenylephrine 3 mg-5 mg-7.5 mg/5 mL oral liquid:
6 to 11 yrs: 2.5 to 5 mL orally every 4 to 6 hours not to exceed 20 mL daily
12 yrs or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.


What other drugs will affect chlorpheniramine, hydrocodone, and phenylephrine?


Before using this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by chlorpheniramine, hydrocodone, and phenylephrine.

Tell your doctor about all other medications you use, especially:



  • blood pressure medication;




  • cimetidine (Tagamet);




  • rifampin (Rifadin, Rifater, Rifamate, Rimactane);




  • zidovudine (Retrovir, AZT);




  • an antidepressant;




  • a diuretic (water pill);




  • medication to treat irritable bowel syndrome;




  • bladder or urinary medications such as oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol);




  • aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);




  • seizure medication such as phenytoin (Dilantin) or phenobarbital (Luminal, Solfoton);




  • a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others; or




  • medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), haloperidol (Haldol), mesoridazine (Serentil), pimozide (Orap), or thioridazine (Mellaril).



This list is not complete and other drugs may interact with chlorpheniramine, hydrocodone, and phenylephrine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More chlorpheniramine, hydrocodone, and phenylephrine resources


  • Chlorpheniramine, hydrocodone, and phenylephrine Side Effects (in more detail)
  • Chlorpheniramine, hydrocodone, and phenylephrine Dosage
  • Chlorpheniramine, hydrocodone, and phenylephrine Use in Pregnancy & Breastfeeding
  • Chlorpheniramine, hydrocodone, and phenylephrine Drug Interactions
  • Chlorpheniramine, hydrocodone, and phenylephrine Support Group
  • 4 Reviews for Chlorpheniramine, hydrocodone, and phenylephrine - Add your own review/rating


Compare chlorpheniramine, hydrocodone, and phenylephrine with other medications


  • Cough and Nasal Congestion


Where can I get more information?


  • Your pharmacist can provide more information about chlorpheniramine, hydrocodone, and phenylephrine.

See also: chlorpheniramine, hydrocodone, and phenylephrine side effects (in more detail)


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Tuesday, June 26, 2012

valacyclovir


val-ay-SYE-kloe-vir


Commonly used brand name(s)

In the U.S.


  • Valtrex

Available Dosage Forms:


  • Tablet

Therapeutic Class: Antiviral


Pharmacologic Class: Viral DNA Polymerase Inhibitor


Chemical Class: Guanosine Nucleoside Analog


Uses For valacyclovir


Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. It is also used to treat chickenpox and cold sores in children.


In your body, valacyclovir becomes the anti-herpes medicine, acyclovir. Although valacyclovir will not cure shingles or genital herpes, it does help relieve the pain and discomfort and helps the sores heal faster.


Valacyclovir is available only with your doctor's prescription.


Before Using valacyclovir


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For valacyclovir, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to valacyclovir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of valacyclovir in children below 12 years of age with cold sores, and children below 2 years of age with chickenpox. Safety and efficacy have not been established.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of valacyclovir in the elderly. However, elderly patients are more likely to have age-related kidney disease, which may require an adjustment in the dose of patients receiving valacyclovir.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersBAnimal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking valacyclovir, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using valacyclovir with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Mycophenolate Mofetil

  • Mycophenolic Acid

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of valacyclovir. Make sure you tell your doctor if you have any other medical problems, especially:


  • Advanced human immunodeficiency virus (HIV) infection or

  • Bone marrow transplantation or

  • Kidney transplantation—Patients with these medical problems may have an increased risk of severe side effects.

  • Kidney disease—The effects may be increased because of slower removal of valacyclovir from the body.

Proper Use of valacyclovir


Valacyclovir works best if it is used within 48 hours after the first symptoms of shingles or genital herpes (e.g., pain, burning, or blisters) begin to appear. For recurrent outbreaks of genital herpes, valacyclovir works best if it is used within 24 hours after the symptoms begin to appear.


If you are taking valacyclovir for the treatment of chickenpox, it is best to start taking valacyclovir as soon as possible after the first sign of the chickenpox rash appears, usually within one day.


Valacyclovir may be taken with meals or on an empty stomach.


If you are using the oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.


Drink extra fluids so you will pass more urine while you are using valacyclovir. This will keep your kidneys working well and help prevent kidney problems.


To help clear up your infection, keep taking valacyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use valacyclovir more often or for a longer time than your doctor ordered.


Dosing


The dose of valacyclovir will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of valacyclovir. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For oral dosage form (tablets):
    • For treatment of chickenpox:
      • Adults and children below 2 years of age—Use and dose must be determined by your doctor.

      • Children 2 to 18 years of age—Dose is based on body weight and must be determined by your doctor. The usual dose is 20 milligrams (mg) per kilogram (kg) of body weight, taken three times a day for 5 days. However, the dose is usually not more than 1000 mg three times a day.


    • For treatment of cold sores:
      • Adults—2000 milligrams (mg) every 12 hours for one day.

      • Children 12 years of age and above—2000 milligrams (mg) every 12 hours for one day.

      • Children below 12 years of age—Use and dose must be determined by your doctor.


    • For treatment of genital herpes, first outbreak:
      • Adults—1000 milligrams (mg) two times a day for ten days.

      • Children—Use and dose must be determined by your doctor.


    • For treatment of genital herpes, recurrent outbreaks:
      • Adults—500 milligrams (mg) two times a day for three days.

      • Children—Use and dose must be determined by your doctor.


    • To prevent recurrent outbreaks of genital herpes:
      • Adults—500 milligrams (mg) or 1000 mg once a day.

      • Children—Use and dose must be determined by your doctor.


    • For treatment of shingles:
      • Adults—1000 milligrams (mg) three times a day for seven days.

      • Children—Use and dose must be determined by your doctor.



Missed Dose


If you miss a dose of valacyclovir, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions While Using valacyclovir


If you or your child's symptoms do not improve within a few days, or if they become worse, check with your doctor.


The areas affected by genital herpes, chickenpox, or shingles should be kept as clean and dry as possible. Also, wear loose-fitting clothing to avoid irritating the sores (blisters).


It is important to remember that valacyclovir will not keep you from spreading herpes to others.


Herpes infection of the genitals can be caught from or spread to your partner during any sexual activity. Even though you may get herpes if your partner has no symptoms, the infection is more likely to be spread if sores are present. This is true until the sores are completely healed and the scabs have fallen off. Therefore, it is best to avoid any sexual activity if either you or your sexual partner has any symptoms of herpes. The use of a latex condom (“rubber") may help prevent the spread of herpes. However, spermicidal (sperm-killing) jelly or a diaphragm will probably not help.


valacyclovir Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor immediately if any of the following side effects occur:


More common
  • Discouragement

  • feeling sad or empty

  • irritability

  • lack of appetite

  • loss of interest or pleasure

  • tiredness

  • trouble concentrating

  • trouble sleeping

Rare
  • Black, tarry stools

  • chest pain

  • chills

  • cough

  • decreased frequency or output of urine

  • fever

  • flu-like symptoms

  • headache

  • lower back or side pain

  • reduced mental alertness

  • shortness of breath

  • yellow eyes or skin

Incidence not known
  • Actions that are out of control

  • agitation

  • anxiety

  • back, leg, or stomach pains

  • bleeding gums

  • blood in urine or stools

  • blurred vision

  • change in consciousness

  • change in mental status

  • changes in behavior, especially in interactions with other people

  • changes in patterns and rhythms of speech

  • dark or bloody urine

  • difficult or labored breathing

  • difficulty speaking

  • difficulty swallowing

  • dizziness

  • drowsiness

  • dry mouth

  • fast, pounding, or irregular heartbeat or pulse

  • feeling that others are watching you or controlling your behavior

  • feeling that others can hear your thoughts

  • feeling, seeing, or hearing things that are not there

  • general tiredness and weakness

  • hyperventilation

  • increased thirst

  • itching

  • lightheadedness when getting up from a lying or sitting position

  • light-colored stools

  • loss of consciousness

  • mood or mental changes

  • nausea and vomiting

  • nervousness

  • pale color of skin

  • pinpoint red spots on the skin

  • pounding in the ears

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • redness of the skin

  • restlessness

  • seeing, hearing, or feeling things that are not there

  • seizures

  • severe mood or mental changes

  • shakiness and unsteady walk

  • shakiness in the legs, arms, hands, or feet

  • skin rash

  • slurred speech

  • sores, ulcers, or white spots on the lips or in the mouth

  • stiff neck

  • swelling of the face, fingers, or lower legs

  • swollen or painful glands

  • talking, feeling, and acting with excitement

  • tightness in the chest

  • trembling or shaking of the hands or feet

  • trouble in speaking

  • troubled breathing

  • unsteadiness, trembling, or other problems with muscle control or coordination

  • unusual behavior

  • unusual bleeding or bruising

  • unusual tiredness or weakness

  • upper right abdominal pain

  • vomiting

  • weight gain

  • wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Body aches or pain

  • cramps

  • difficulty in moving

  • ear congestion

  • heavy bleeding

  • loss of voice

  • muscle aches

  • muscle pain or stiffness

  • nasal congestion

  • pain

  • pain in joints

  • sneezing

  • sore throat

  • stuffy or runny nose

Less common
  • Constipation

  • diarrhea

Incidence not known
  • Blistering, peeling, or loosening of the skin

  • hair loss or thinning of the hair

  • hives or welts

  • increased sensitivity of skin to sunlight

  • red, irritated eyes

  • redness or other discoloration of the skin

  • severe sunburn

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: valacyclovir side effects (in more detail)



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More valacyclovir resources


  • Valacyclovir Side Effects (in more detail)
  • Valacyclovir Dosage
  • Valacyclovir Use in Pregnancy & Breastfeeding
  • Drug Images
  • Valacyclovir Drug Interactions
  • Valacyclovir Support Group
  • 62 Reviews for Valacyclovir - Add your own review/rating


  • Valacyclovir MedFacts Consumer Leaflet (Wolters Kluwer)

  • Valacyclovir Prescribing Information (FDA)

  • Valacyclovir Hydrochloride Monograph (AHFS DI)

  • Valtrex Prescribing Information (FDA)

  • Valtrex Consumer Overview



Compare valacyclovir with other medications


  • Cold Sores
  • Cytomegalovirus Infection
  • Herpes Simplex, Mucocutaneous/Immunocompetent Host
  • Herpes Simplex, Mucocutaneous/Immunocompromised Host
  • Herpes Simplex, Suppression
  • Herpes Zoster
  • Multiple Sclerosis
  • Varicella-Zoster

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Thursday, June 21, 2012

Ethedent Chewable


Generic Name: fluoride (FLOR ide)

Brand Names: Altaflor, Ethedent Chewable, Fluor-A-Day, Fluoritab, Flura-Drops, Flura-Loz, Flura-Tab, Karidium, Lozi-Flur, Luride, Nafrinse, Pharmaflur, Pharmaflur 1.1


What is Ethedent Chewable (fluoride)?

Fluoride is a substance that strengthens tooth enamel. This helps to prevent dental cavities.


Fluoride is used as a medication to prevent tooth decay in people that have a low level of fluoride in their drinking water. Fluoride is also used to prevent tooth decay in people who undergo radiation of the head and/or neck, which may cause dryness of the mouth and an increased incidence of tooth decay.


Fluoride may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Ethedent Chewable (fluoride)?


You should not use fluoride if the level of fluoride in your drinking water is greater than 0.7 parts per million (ppm).

Before using fluoride, tell your dentist and doctor if you are on a low salt or a salt free diet. You may not be able to use fluoride, or you may need special tests while you are using it.


Do not take fluoride with milk, other dairy products, or calcium supplements. Calcium can make it harder for your body to absorb fluoride.

Avoid using antacids without your doctor's advice. Use only the specific type of antacid your doctor recommends. Many antacids contain calcium, which can interfere with fluoride absorption.


What should I discuss with my healthcare provider before taking Ethedent Chewable (fluoride)?


You should not use fluoride if the level of fluoride in your drinking water is greater than 0.7 parts per million (ppm).

Before using fluoride, tell your dentist and doctor if you are on a low salt or a salt free diet. You may not be able to use fluoride, or you may need special tests while you are using it.


Talk to your doctor and dentist before taking fluoride if you are pregnant or could become pregnant during treatment. Talk to your doctor and dentist before taking fluoride if you are breast-feeding. The American Dental Association's Council on Dental Therapeutics recommends the use of fluoride by children up to 13 years of age; the American Academy of Pediatrics recommends fluoride supplementation by children until the age of 16 years of age. Do not give a 1-mg tablet to a child younger than 3 years old, or when your drinking water fluoride content is equal to or greater than 0.3 ppm.

How should I take Ethedent Chewable (fluoride)?


Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.


Take this medicine with a full glass of water. Do not take fluoride with milk or other dairy products. Calcium can make it harder for your body to absorb fluoride.

Suck on the fluoride lozenge until it dissolves completely in your mouth. Do not chew the lozenge or swallow it whole.


The chewable forms of fluoride can be chewed, swallowed, dissolved in the mouth, added to drinking water or fruit juice, or added to water for use in infant formula or other food.


The fluoride drops can be taken by mouth undiluted, or mixed with fluid or food.


If you mix fluoride with food or water, drink or eat this mixture right away. Do not save it for later use.


It is important to take fluoride regularly to get the most benefit.


Store fluoride at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include nausea, vomiting, stomach pain, diarrhea, drooling, numbness or tingling, loss of feeling anywhere in your body, muscle stiffness, or seizure (convulsions).


What should I avoid while taking Ethedent Chewable (fluoride)?


Do not take fluoride with milk, other dairy products, or calcium supplements. Calcium can make it harder for your body to absorb fluoride.

Avoid using antacids without your doctor's advice. Use only the specific type of antacid your doctor recommends. Many antacids contain calcium, which can interfere with fluoride absorption.


Ethedent Chewable (fluoride) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor if you have any of the following side effects:

  • discolored teeth;




  • weakened tooth enamel; or




  • any changes in the appearance of your teeth.



Less serious side effects may include:



  • stomach upset;




  • headache; or




  • weakness.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Ethedent Chewable (fluoride)?


There may be other drugs that can interact with fluoride. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Ethedent Chewable resources


  • Ethedent Chewable Use in Pregnancy & Breastfeeding
  • 0 Reviews for Ethedent Chewable - Add your own review/rating


  • Epiflur Prescribing Information (FDA)

  • Fluor-A-Day Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Fluor-A-Day Advanced Consumer (Micromedex) - Includes Dosage Information

  • Fluor-a-Day Prescribing Information (FDA)

  • Fluorides Monograph (AHFS DI)

  • Fluoritab Drops MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lozi-Flur Lozenges MedFacts Consumer Leaflet (Wolters Kluwer)



Compare Ethedent Chewable with other medications


  • Prevention of Dental Caries


Where can I get more information?


  • Your pharmacist can provide more information about fluoride.


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Monday, June 18, 2012

Methylprednisolone Solution



Pronunciation: METH-il-pred-NIS-oh-lone
Generic Name: Methylprednisolone
Brand Name: Examples include A-methapred and Solu-Medrol


Methylprednisolone Solution is used for:

Treating certain conditions associated with decreased adrenal gland function. It is also used to treat severe inflammation caused by certain conditions, including severe asthma, severe allergies, rheumatoid arthritis, ulcerative colitis, certain blood disorders, lupus, multiple sclerosis, and certain eye and skin conditions. It may also be used for other conditions as determined by your doctor.


Methylprednisolone Solution is a corticosteroid. It works by modifying the body's immune response to various conditions and decreasing inflammation.


Do NOT use Methylprednisolone Solution if:


  • you are allergic to any ingredient in Methylprednisolone Solution

  • you are presently taking mifepristone

  • the patient is a premature infant

  • you have a systemic fungal infection

  • you are scheduled to have a live vaccine (eg, smallpox vaccine)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Methylprednisolone Solution:


Some medical conditions may interact with Methylprednisolone Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of bleeding problems, heart problems (eg, congestive heart failure, recent heart attack), high blood pressure, kidney problems, liver problems (eg, cirrhosis), low blood potassium levels, diabetes, seizures, an underactive or overactive thyroid, adrenal gland problems, fluid retention (eg, swelling of the hands, ankles, or feet), or any mental or mood problems

  • if you have recently had a fungal, bacterial, viral, or other type of infection; herpes infection of the eye or other eye problems (eg, glaucoma, cataracts); chickenpox; measles; or shingles

  • if you have HIV infection or tuberculosis (TB), or you have ever had a positive TB skin test

  • if you have any stomach problems (eg, ulcers), intestinal problems (eg, blockage, perforation, infection, unexplained diarrhea, diverticulitis, ulcerative colitis), or inflammation of the esophagus, or you have had recent intestinal surgery

  • if you have weak bones (eg, osteoporosis), muscle problems (eg, myasthenia gravis), or recent head trauma

  • if you have had any recent vaccinations (eg, smallpox)

Some MEDICINES MAY INTERACT with Methylprednisolone Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Aprepitant, azole antifungals (eg, itraconazole, ketoconazole), clarithromycin, cyclosporine, diltiazem, neostigmine, or troleandomycin because side effects, such as adrenal gland or nervous system problems (eg, seizures) or severe muscle weakness, may occur

  • Estrogens (eg, oral contraceptives) and macrolide antibiotics (eg, erythromycin) because they may increase the risk of Methylprednisolone Solution's side effects

  • Aminoglutethimide, barbiturates (eg, phenobarbital), carbamazepine, cholestyramine, hydantoins (eg, phenytoin), lithium, or rifampin because they may decrease Methylprednisolone Solution's effectiveness

  • Amphotericin B, aspirin, digoxin, live vaccines, mifepristone, potassium-depleting diuretics (eg, furosemide), quinolone antibiotics (eg, ciprofloxacin), or ritodrine because the risk of their side effects may be increased by Methylprednisolone Solution

  • Aldesleukin, oral anticoagulants (eg, warfarin), antidiabetic medications (eg, glipizide), isoniazid, salicylates (eg, aspirin), or certain skin tests (eg, skin allergy tests) because their effectiveness may be decreased by Methylprednisolone Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Methylprednisolone Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Methylprednisolone Solution:


Use Methylprednisolone Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Methylprednisolone Solution is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Methylprednisolone Solution at home, a health care provider will teach you how to use it. Be sure you understand how to use Methylprednisolone Solution. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.

  • Do not use Methylprednisolone Solution if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.

  • Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.

  • If you miss a dose of Methylprednisolone Solution, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Methylprednisolone Solution.



Important safety information:


  • Methylprednisolone Solution may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.

  • If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.

  • Tell your doctor or dentist that you take Methylprednisolone Solution before you receive any medical or dental care, emergency care, or surgery.

  • Diabetes patients - Methylprednisolone Solution may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Talk with your doctor before you receive any vaccine while you are using Methylprednisolone Solution.

  • Methylprednisolone Solution may have benzyl alcohol in it. Do not use medicine with benzyl alcohol in NEWBORNS or INFANTS. It may cause serious and sometimes fatal nervous system problems and other side effects. Check with your doctor or pharmacist to see if your product has benzyl alcohol in it.

  • Lab tests, including adrenal function, blood pressure monitoring, and eye exams, may be performed while you use Methylprednisolone Solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Methylprednisolone Solution may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Methylprednisolone Solution for a few days before the tests.

  • Corticosteroids may affect growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they use Methylprednisolone Solution.

  • Methylprednisolone Solution should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Methylprednisolone Solution while you are pregnant. It is not known if Methylprednisolone Solution is found in breast milk. If you are or will be breast-feeding while you use Methylprednisolone Solution, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Methylprednisolone Solution:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; facial flushing; headache; increased sweating; mild nausea; pain, swelling, or redness at the injection site; stomach pain or bloating; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody, black, or tarry stools; changes in body fat; changes in menstrual period; chest pain; fainting; fever, chills, or sore throat; increased hunger, thirst, or urination; mental or mood changes (eg, depression, personality or behavioral changes); muscle pain, weakness, or wasting; seizures; severe nausea or vomiting; shortness of breath; slow, fast, or irregular heartbeat; slow wound healing; stomach pain; sudden, severe dizziness or headache; swelling of the feet or legs; tendon, bone, or joint pain; thinning or discoloration of the skin; unusual bruising or bleeding; unusual skin sensation; unusual weight gain; vision changes or other eye problems; vomit that looks like coffee grounds.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.



If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; fever; loss of appetite; muscle pain or weakness; nausea; seizures; severe dizziness.


Proper storage of Methylprednisolone Solution:

Methylprednisolone Solution is usually handled and stored by a health care provider. If you are using Methylprednisolone Solution at home, store Methylprednisolone Solution as directed by your pharmacist or health care provider. Keep Methylprednisolone Solution out of the reach of children and away from pets.


General information:


  • If you have any questions about Methylprednisolone Solution, please talk with your doctor, pharmacist, or other health care provider.

  • Methylprednisolone Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Methylprednisolone Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Methylprednisolone resources


  • Methylprednisolone Use in Pregnancy & Breastfeeding
  • Drug Images
  • Methylprednisolone Drug Interactions
  • Methylprednisolone Support Group
  • 41 Reviews for Methylprednisolone - Add your own review/rating


Compare Methylprednisolone with other medications


  • Adrenogenital Syndrome
  • Asthma
  • Asthma, acute
  • Asthma, Maintenance
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  • Dermatologic Lesion
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  • Hay Fever
  • Immunosuppression
  • Inflammatory Conditions
  • Neuralgia
  • Osteoarthritis
  • Rheumatoid Arthritis
  • Shock

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Ah-Chew D


Generic Name: phenylephrine (FEN il EFF rin)

Brand Names: Ah-Chew D, Dimetapp Cold Drops, Lusonal, Nasop, Nasop12, PediaCare Children's Decongestant, Phenyl-T, Sudafed PE, Sudafed PE Children's Nasal Decongestant, Sudafed PE Quick Dissolve, Sudogest PE, Triaminic Thin Strips Cold


What is Ah-Chew D (phenylephrine)?

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).


Phenylephrine is used to treat nasal congestion and sinus pressure caused by allergies, the common cold, or the flu. Phenylephrine may be used to treat congestion of the tubes that drain fluid from your inner ears, called the eustachian (yoo-STAY-shun) tubes.


Phenylephrine may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Ah-Chew D (phenylephrine)?


Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

You should not use this medication if you are allergic to phenylephrine.


Do not use phenylephrine if you have used linezolid (Zyvox) or procarbazine (Matulane), or if you have taken a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life-threatening side effects can occur if you take phenylephrine before these other drugs have cleared from your body.


Before you take phenylephrine, tell your doctor if you are allergic to any decongestants, or if you have heart disease, heart rhythm disorder, high blood pressure, circulation problems, diabetes, glaucoma, a thyroid disorder, kidney disease, an enlarged prostate or urination problems, anxiety, sleep problems, bipolar disorder or other mental illness.


Phenylephrine may interact with heart or blood pressure medications, antidepressants, diabetes medications, migraine headache medications, and other decongestants.


Never take more of the medicine than directed on the label or prescribed by your doctor.


Call your doctor if your symptoms do not improve after 7 days of using phenylephrine, or if they get worse and your also have a fever.

What should I discuss with my healthcare provider before taking Ah-Chew D (phenylephrine)?


You should not use this medication if you are allergic to phenylephrine.


Do not use phenylephrine if you have used linezolid (Zyvox) or procarbazine (Matulane), or if you have taken a monoamine oxidase inhibitor (MAOI) such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) in the last 14 days. Serious, life-threatening side effects can occur if you take phenylephrine before these other drugs have cleared from your body.


If you have certain conditions, you may need a dose adjustment or special tests to safely use this medication. Before you take phenylephrine, tell your doctor if you are allergic to any decongestants, or if you have:



  • heart disease, heart rhythm disorder;




  • high blood pressure;




  • circulation problems (such as Raynaud's syndrome);




  • diabetes;




  • glaucoma;




  • a thyroid disorder;



  • kidney disease;


  • an enlarged prostate or urination problems;




  • sleep problems, anxiety; or




  • mental illness such as bipolar disorder.




FDA pregnancy category C. Is not known whether this medication will harm an unborn baby. Before you take phenylephrine, tell doctor if you are pregnant. Phenylephrine may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Older adults may be more likely to have side effects from this medication.

Disintegrating and liquid forms of cold medicine may contain sugar or artificial sweeteners (phenylalanine). This would be important to know if you have diabetes or phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about sugar or phenylalanine.


How should I use Ah-Chew D (phenylephrine)?


Use this medication exactly as directed on the label, or as it has been prescribed by your doctor. Do not use the medication in larger amounts, or use it for longer than recommended. Cold medicine is usually taken only for a short time until your symptoms clear up.


Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. You may take phenylephrine with food if it upsets your stomach. Take the phenylephrine tablet with a full glass of water.

Measure the liquid form of phenylephrine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


The chewable phenylephrine tablet must be chewed thoroughly before you swallow it.


To use the phenylephrine disintegrating strip, place one strip on your tongue and allow it to dissolve without chewing.


To use the disintegrating tablet, make sure your hands are dry and peel back the foil from the blister package. Place the tablet on your tongue. It will begin to dissolve right away. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.


Phenylephrine is usually taken every 4 hours. Follow the directions on the medicine label. Never take more of the medicine than directed on the label or prescribed by your doctor.


Call your doctor if your symptoms do not improve after 7 days of using phenylephrine, or if they get worse and your also have a fever.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.


Store phenylephrine at room temperature away from moisture and heat. Keep the disintegrating tablets or strips in their package until you are ready to take one.

Throw away any unused phenylephrine after the expiration date on the label has passed. Do not flush this medication down a toilet. Ask your pharmacist about the safest way to dispose of unused medicines.


What happens if I miss a dose?


Cold medicine is usually taken only as needed, so you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, severe dizziness, sweating, vomiting, hallucinations, fast or uneven heart rate, fainting, seizure (convulsions), and weak or shallow breathing.


What should I avoid while using Ah-Chew D (phenylephrine)?


Do not use any other over-the-counter cold, allergy, or cough medication without first asking your doctor or pharmacist. Phenylephrine is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much phenylephrine. Read the label of any other medicine you are using to see if it contains phenylephrine or another decongestant.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.


Avoid smoking. It can add to the effects of phenylephrine in decreasing blood flow, which can lead to uncomfortable symptoms. Avoid drinking alcohol while you are taking phenylephrine.

Ah-Chew D (phenylephrine) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using phenylephrine and call your doctor at once if you have a serious side effect such as:

  • severe dizziness, restless feeling, nervousness, or insomnia;




  • unusual thoughts or behavior;




  • feeling like you might pass out;




  • fast, pounding, or uneven heartbeat;




  • tremors or shaking;




  • numbness, tingling, or cold feeling in your hands or feet; or




  • urinating less than usual or not at all.



Less serious side effects may include:



  • headache, dizziness;




  • feeling excited or restless (especially in children);




  • upset stomach; or




  • mild sleep problems.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Ah-Chew D (phenylephrine)?


Tell your doctor about all other medications you use, especially:



  • other decongestants, including nasal sprays;




  • digoxin (digitalis, Lanoxin);




  • medicine to treat diabetes;




  • medicines to treat high blood pressure such as reserpine, methyldopa (Aldomet), and others;




  • migraine headache medicine such as ergotamine (Ergomar), naratriptan (Amerge), sumatriptan (Imitrex) or zolmitriptan (Zomig);




  • an antidepressant such as amitriptyline (Elavil), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others;




  • a beta-blocker such as atenolol (Tenormin), carvedilol (Coreg), metoprolol (Lopressor, Toprol), propranolol (Inderal), sotalol (Betapace), and others; or




  • a calcium channel blocker such as amlodipine (Norvasc), diltiazem (Tiazac, Cartia, Cardizem), felodipine (Plendil), nifedipine (Procardia, Adalat), verapamil (Calan, Covera, Isoptin, Verelan), and others.



This list is not complete and there may be other drugs that can interact with phenylephrine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.



More Ah-Chew D resources


  • Ah-Chew D Side Effects (in more detail)
  • Ah-Chew D Use in Pregnancy & Breastfeeding
  • Ah-Chew D Drug Interactions
  • Ah-Chew D Support Group
  • 0 Reviews for Ah-Chew D - Add your own review/rating


  • AH-Chew D Chewable Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lusonal Liquid MedFacts Consumer Leaflet (Wolters Kluwer)

  • Nasop Dissolving Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

  • Neo-Synephrine Nasal Advanced Consumer (Micromedex) - Includes Dosage Information

  • Neo-Synephrine MedFacts Consumer Leaflet (Wolters Kluwer)

  • Phenylephrine Hydrochloride Monograph (AHFS DI)

  • Sudafed PE MedFacts Consumer Leaflet (Wolters Kluwer)

  • Sudafed PE Consumer Overview



Compare Ah-Chew D with other medications


  • Nasal Congestion


Where can I get more information?


  • Your pharmacist can provide more information about phenylephrine.

See also: Ah-Chew D side effects (in more detail)


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Friday, June 15, 2012

Acetaminophen/Pheniramine/Phenylephrine Powder Packets


Pronunciation: a-SEET-a-MIN-oh-fen/fen-IR-a-meen/FEN-il-EF-rin
Generic Name: Acetaminophen/Pheniramine/Phenylephrine
Brand Name: Examples include Theraflu Cold and Sore Throat and Theraflu Flu and Sore Throat


Acetaminophen/Pheniramine/Phenylephrine Powder Packets are used for:

Relieving symptoms of colds, hay fever, and allergies such as headache, sinus pain, nasal and sinus congestion, sneezing, watery eyes, runny nose, fever, and itching of the nose or throat. It may also be used for other conditions as determined by your doctor.


Acetaminophen/Pheniramine/Phenylephrine Powder Packets are an antihistamine, decongestant, and pain reliever combination. It works in the brain to relieve pain. It blocks histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. It also shrinks swollen nasal tissue to help relieve congestion.


Do NOT use Acetaminophen/Pheniramine/Phenylephrine Powder Packets if:


  • you are allergic to any ingredient in Acetaminophen/Pheniramine/Phenylephrine Powder Packets

  • you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems

  • you are unable to urinate or are having an asthma attack

  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Acetaminophen/Pheniramine/Phenylephrine Powder Packets:


Some medical conditions may interact with Acetaminophen/Pheniramine/Phenylephrine Powder Packets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of breathing problems (eg, emphysema, asthma); heart disease; diabetes; blood vessel problems; stroke; an enlarged prostate or other prostate problems; glaucoma; high blood pressure; seizures; an overactive thyroid; adrenal gland problems (eg, pheochromocytoma); sleep apnea; stomach problems; blockage of the stomach, intestines, or bladder; or ulcers

  • if you have a history of liver problems (eg, hepatitis) or kidney problems, or if you drink 3 or more alcoholic drinks per day

  • if you have trouble urinating or trouble sleeping

  • if you are on a low-salt (sodium) diet

Some MEDICINES MAY INTERACT with Acetaminophen/Pheniramine/Phenylephrine Powder Packets. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Beta-blockers (eg, propranolol), catechol-o-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, isoniazid, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), sodium oxybate (GHB) , or tricyclic antidepressants (eg, amitriptyline) because the risk of Acetaminophen/Pheniramine/Phenylephrine Powder Packets's side effects may be increased

  • Digoxin or droxidopa because risk of irregular heartbeat or heart attack may be increased

  • Anticoagulants (eg, warfarin), bromocriptine, or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Acetaminophen/Pheniramine/Phenylephrine Powder Packets

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Acetaminophen/Pheniramine/Phenylephrine Powder Packets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetaminophen/Pheniramine/Phenylephrine Powder Packets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Acetaminophen/Pheniramine/Phenylephrine Powder Packets:


Use Acetaminophen/Pheniramine/Phenylephrine Powder Packets as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Acetaminophen/Pheniramine/Phenylephrine Powder Packets by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Dissolve contents of 1 packet in 8 oz of hot water. Sip while hot. Drink entire mixture within 10 to 15 minutes.

  • If using a microwave, stir before and after heating. Do not overheat.

  • If you miss a dose of Acetaminophen/Pheniramine/Phenylephrine Powder Packets and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetaminophen/Pheniramine/Phenylephrine Powder Packets.



Important safety information:


  • Acetaminophen/Pheniramine/Phenylephrine Powder Packets may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Acetaminophen/Pheniramine/Phenylephrine Powder Packets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol while you are taking Acetaminophen/Pheniramine/Phenylephrine Powder Packets.

  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Acetaminophen/Pheniramine/Phenylephrine Powder Packets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Do not take more than the recommended dose or use Acetaminophen/Pheniramine/Phenylephrine Powder Packets for longer than prescribed without checking with your doctor.

  • Severe or persistent sore throat or sore throat accompanied by high fever, headache, nausea, and vomiting may be serious. Consult a doctor promptly. Do not use for sore throat for longer than 2 days unless directed by a doctor.

  • Talk with your doctor if pain or nasal congestion lasts for more than 7 days, gets worse, or occurs with rash or persistent headache.

  • Check with your doctor if fever lasts for more than 3 days or if it gets worse.

  • Check with your doctor if redness or swelling is present, or if new symptoms occur.

  • Acetaminophen/Pheniramine/Phenylephrine Powder Packets has acetaminophen, pheniramine, and phenylephrine in it. Before you start any new medicine, check the label to see if it has acetaminophen, pheniramine, or phenylephrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.

  • Do not take diet or appetite control medicines while you are taking Acetaminophen/Pheniramine/Phenylephrine Powder Packets without checking with your doctor.

  • Acetaminophen/Pheniramine/Phenylephrine Powder Packets may harm your liver. Your risk may be greater if you drink alcohol while you are using Acetaminophen/Pheniramine/Phenylephrine Powder Packets. Talk to your doctor before you take Acetaminophen/Pheniramine/Phenylephrine Powder Packets or other fever reducers if you drink more than 3 drinks with alcohol per day.

  • Acetaminophen/Pheniramine/Phenylephrine Powder Packets may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Acetaminophen/Pheniramine/Phenylephrine Powder Packets for a few days before tests.

  • Acetaminophen/Pheniramine/Phenylephrine Powder Packets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Acetaminophen/Pheniramine/Phenylephrine Powder Packets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • If you have trouble sleeping, ask your doctor or pharmacist about the best time of the day to take Acetaminophen/Pheniramine/Phenylephrine Powder Packets.

  • Use Acetaminophen/Pheniramine/Phenylephrine Powder Packets with caution in the ELDERLY; they may be more sensitive to its effects.

  • Caution is advised when using Acetaminophen/Pheniramine/Phenylephrine Powder Packets in CHILDREN; they may be more sensitive to its effects, especially excitability.

  • Do not use Acetaminophen/Pheniramine/Phenylephrine Powder Packets in CHILDREN younger than 12 years old without checking with the child's doctor; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Acetaminophen/Pheniramine/Phenylephrine Powder Packets can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acetaminophen/Pheniramine/Phenylephrine Powder Packets while you are pregnant. Some of the ingredients in Acetaminophen/Pheniramine/Phenylephrine Powder Packets are found in breast milk. If you are or will be breast-feeding while you use Acetaminophen/Pheniramine/Phenylephrine Powder Packets, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Acetaminophen/Pheniramine/Phenylephrine Powder Packets:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; nausea; nervousness; trouble sleeping.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; dark urine or pale stools; difficulty urinating; fast or irregular heartbeat; hallucinations; rapid pulse; seizures; severe or persistent nervousness, dizziness, headache, or trouble sleeping; stomach pain; tremors; unusual fatigue; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Acetaminophen/Pheniramine/Phenylephrine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fast or irregular heartbeat; fever; hallucinations; nausea; seizures; stomach pain; sweating; tremors; trouble breathing; unusual drowsiness or dizziness; vomiting.


Proper storage of Acetaminophen/Pheniramine/Phenylephrine Powder Packets:

Store Acetaminophen/Pheniramine/Phenylephrine Powder Packets at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetaminophen/Pheniramine/Phenylephrine Powder Packets out of the reach of children and away from pets.


General information:


  • If you have any questions about Acetaminophen/Pheniramine/Phenylephrine Powder Packets, please talk with your doctor, pharmacist, or other health care provider.

  • Acetaminophen/Pheniramine/Phenylephrine Powder Packets are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Acetaminophen/Pheniramine/Phenylephrine Powder Packets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Acetaminophen/Pheniramine/Phenylephrine resources


  • Acetaminophen/Pheniramine/Phenylephrine Side Effects (in more detail)
  • Acetaminophen/Pheniramine/Phenylephrine Use in Pregnancy & Breastfeeding
  • Acetaminophen/Pheniramine/Phenylephrine Drug Interactions
  • Acetaminophen/Pheniramine/Phenylephrine Support Group
  • 0 Reviews for Acetaminophen/Pheniramine/Phenylephrine - Add your own review/rating


Compare Acetaminophen/Pheniramine/Phenylephrine with other medications


  • Cold Symptoms

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Saturday, June 9, 2012

labetalol Intravenous



la-BAYT-a-lol


Commonly used brand name(s)

In the U.S.


  • Normodyne

  • Trandate

Available Dosage Forms:


  • Solution

Therapeutic Class: Antihypertensive


Pharmacologic Class: Alpha/Beta-Adrenergic Blocker


Uses For labetalol


Labetalol injection is used to treat severe high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled .


labetalol is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart .


labetalol is available only with your doctor's prescription .


Before Using labetalol


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For labetalol, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to labetalol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of labetalol injection in the pediatric population. Safety and efficacy have not been established .


Geriatric


No information is available on the relationship of age to the effects of labetalol in geriatric patients. However, elderly patients are more likely to have age-related liver and heart problems, which may require an adjustment in the dose for patients receiving labetalol injection .


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving labetalol, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.


Using labetalol with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Albuterol

  • Amiodarone

  • Arformoterol

  • Bambuterol

  • Bitolterol

  • Broxaterol

  • Clenbuterol

  • Colterol

  • Diltiazem

  • Dronedarone

  • Fenoldopam

  • Fenoterol

  • Formoterol

  • Halothane

  • Hexoprenaline

  • Indacaterol

  • Isoetharine

  • Levalbuterol

  • Metaproterenol

  • Pirbuterol

  • Procaterol

  • Reproterol

  • Rimiterol

  • Ritodrine

  • Salmeterol

  • Terbutaline

  • Tretoquinol

  • Tulobuterol

  • Verapamil

Using labetalol with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.


  • Acarbose

  • Aceclofenac

  • Acemetacin

  • Acetohexamide

  • Alclofenac

  • Alfuzosin

  • Amlodipine

  • Apazone

  • Arbutamine

  • Benfluorex

  • Benoxaprofen

  • Bromfenac

  • Bufexamac

  • Bunazosin

  • Carprofen

  • Chlorpropamide

  • Cimetidine

  • Clometacin

  • Clonixin

  • Dexketoprofen

  • Diclofenac

  • Diflunisal

  • Digoxin

  • Dipyrone

  • Doxazosin

  • Droxicam

  • Enflurane

  • Epinephrine

  • Etodolac

  • Etofenamate

  • Felbinac

  • Felodipine

  • Fenbufen

  • Fenoprofen

  • Fentiazac

  • Floctafenine

  • Flufenamic Acid

  • Flurbiprofen

  • Gliclazide

  • Glimepiride

  • Glipizide

  • Gliquidone

  • Glyburide

  • Guar Gum

  • Ibuprofen

  • Indomethacin

  • Indoprofen

  • Insulin

  • Insulin Aspart, Recombinant

  • Insulin Glulisine

  • Insulin Lispro, Recombinant

  • Iobenguane I 131

  • Isoflurane

  • Isoxicam

  • Ketoprofen

  • Ketorolac

  • Lacidipine

  • Lercanidipine

  • Lornoxicam

  • Magnesium Sulfate

  • Manidipine

  • Meclofenamate

  • Mefenamic Acid

  • Meloxicam

  • Metformin

  • Mibefradil

  • Miglitol

  • Moxisylyte

  • Nabumetone

  • Naproxen

  • Nicardipine

  • Nifedipine

  • Niflumic Acid

  • Nilvadipine

  • Nimesulide

  • Nimodipine

  • Nisoldipine

  • Nitrendipine

  • Oxaprozin

  • Oxyphenbutazone

  • Phenoxybenzamine

  • Phentolamine

  • Phenylbutazone

  • Pirazolac

  • Piroxicam

  • Pirprofen

  • Pranidipine

  • Prazosin

  • Propyphenazone

  • Proquazone

  • Repaglinide

  • St John's Wort

  • Sulindac

  • Suprofen

  • Tamsulosin

  • Tenidap

  • Tenoxicam

  • Terazosin

  • Tiaprofenic Acid

  • Tolazamide

  • Tolbutamide

  • Tolmetin

  • Trimazosin

  • Troglitazone

  • Urapidil

  • Zomepirac

Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of labetalol. Make sure you tell your doctor if you have any other medical problems, especially:


  • Angina (severe chest pain)—May provoke chest pain if stopped too quickly .

  • Asthma or

  • Bradycardia (slow heartbeat) or

  • Heart block or

  • Heart failure or

  • Low blood pressure, severe and prolonged—Should not use in patients with these conditions .

  • Diabetes or

  • Hypoglycemia (low blood sugar)—May cover up some of the signs and symptoms of these diseases, such as a fast heartbeat .

  • Liver disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body .

  • Lung disease (e.g., bronchitis, emphysema)—May cause difficulty with breathing in patients with this condition .

  • Pheochromocytoma (adrenal gland tumor)—Use with caution. May require an increased dose .

Proper Use of labetalol


A nurse or other trained health professional will give you labetalol. labetalol is given through a needle placed in one of your veins .


Precautions While Using labetalol


Your doctor will only give you a few doses of labetalol, and then you will be switched to an oral medicine that works the same way. If you have any concerns about this, talk to your doctor .


labetalol Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor or nurse immediately if any of the following side effects occur:


More common
  • Dizziness

  • tingling of the scalp or skin

Less common
  • Abdominal or stomach pain

  • black, tarry stools

  • blurred vision

  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

  • chills

  • clay-colored stools

  • confusion

  • dark urine

  • diarrhea

  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly

  • fast, pounding, or irregular heartbeat or pulse

  • feeling of constant movement of self or surroundings

  • fever

  • general tiredness and weakness

  • headache

  • itching skin

  • light-colored stools

  • loss of appetite

  • nausea and vomiting

  • palpitations

  • sensation of spinning

  • skin rash

  • sweating

  • unpleasant breath odor

  • unusual tiredness or weakness

  • vomiting of blood

  • wheezing

  • yellow eyes or skin

Rare
  • Chest pain or discomfort

  • cough

  • difficult or labored breathing

  • difficulty swallowing

  • hives or welts

  • hoarseness

  • irritation

  • joint pain, stiffness, or swelling

  • large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

  • lightheadedness, dizziness, or fainting

  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue

  • redness of skin

  • shortness of breath

  • slow heartbeat

  • swelling of eyelids, face, lips, hands, or feet

  • tightness in chest

  • troubled breathing or swallowing

Get emergency help immediately if any of the following symptoms of overdose occur:


Symptoms of overdose
  • Convulsions

  • dilated neck veins

  • extreme fatigue

  • irregular breathing

  • loss of bladder control

  • muscle spasm or jerking of all extremities

  • noisy breathing

  • sudden loss of consciousness

  • weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common
  • Stuffy nose

Less common
  • Acid or sour stomach

  • belching

  • change in taste or bad, unusual, or unpleasant (after) taste

  • decreased interest in sexual intercourse

  • heartburn

  • inability to have or keep an erection

  • increased yawning

  • indigestion

  • loss in sexual ability, desire, drive, or performance

  • sleepiness or unusual drowsiness

  • stomach discomfort or upset

  • vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: labetalol Intravenous side effects (in more detail)



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More labetalol Intravenous resources


  • Labetalol Intravenous Side Effects (in more detail)
  • Labetalol Intravenous Use in Pregnancy & Breastfeeding
  • Drug Images
  • Labetalol Intravenous Drug Interactions
  • Labetalol Intravenous Support Group
  • 2 Reviews for Labetalol Intravenous - Add your own review/rating


Compare labetalol Intravenous with other medications


  • High Blood Pressure
  • Hypertensive Emergency
  • Mitral Valve Prolapse
  • Pheochromocytoma

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