Prestim Tablets
10 mg timolol maleate
2.5 mg bendroflumethiazide
Read all of this leaflet carefully before you start taking this medicine.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
- This medicine has been prescribed for you. Do not pass it on to others. It may harm them, even if their symptoms are the same as yours.
- If you experience any side effect and this becomes serious, tell your doctor or pharmacist.
In this leaflet:
1. What Prestim is and what it is used for
2. Before you take Prestim Tablets
3. How to take Prestim Tablets
4. Possible side effects
5. How to store Prestim Tablets
6. Further information
What Prestim Is And What It Is Used For
Prestim Tablets are a combination of two medicines, one slows your heart rate and the other increases water removal from your body.
Prestim tablets are used to treat raised blood pressure.Your doctor has prescribed these tablets for you because your blood pressure is too high.
Before You Take Prestim Tablets
Do not take Prestim Tablets if you:
- Are allergic (hypersensitive) to timolol maleate, bendroflumethiazide, any of the other ingredients of Prestim (these are listed in section 6, “Further Information”), or any medicine known as a thiazide diuretic.
- Have bronchial asthma or a chronic lung disease.
- Have a history of wheezing or asthma.
- Have serious kidney problems.
- Have difficulty urinating.
- Have uncontrolled heart failure, a very slow heart rate, other heart problems or a certain type of angina called Prinzmetal’s angina.
- Have low blood pressure or problems with your blood circulation.
- Have a condition affecting your adrenal glands called phaeochromocytoma.
- Have a condition that causes acidity of the blood called metabolic acidosis.
- Are taking medicines used for relieving depression such as lithium, monoamine oxidase inhibitors (e.g. selegiline, moclobedine) and tricyclic antidepressants (e.g. amitriptyline, lofepramine).
- Are pregnant, or think that you might be pregnant.
Take special care with Prestim Tablets
Tell your doctor before you start treatment if you have or have had in the past one of the following problems or if you develop any of these during treatment:
- Suffer from diabetes, low blood sugar levels (hypoglycaemia), heart, liver or kidney problems.
- Suffer from an overactive thyroid gland.
- Psoriasis (this is a skin disease with thickened patches of red skin, often with silvery scales).
Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
This is extremely important, as using more than one medicine at the same time can strengthen or weaken the effect of the medicines.
In particular, tell your doctor if you are taking any of the following:
- Any other medicines for high blood pressure or heart problems such as: lignocaine, verapamil, disopyramide, tocainide, diltiazem, quinidine, amiodarone, clonidine, digitalis glycosides, reserpine, hydralazine, guanethidine, dihydropyridine derivatives (e.g. nifedipine) and any of the medicines known as class I antiarrhythmic agents.
- Medicines used for treating depression (e.g. lithium, tricyclic antidepressants and monoamine oxidase inhibitors) or other mental problems (e.g. phenothiazines).
- Medicines known as barbiturates, used to treat sleeping disorders.
- An anti-ulcer medicine called cimetidine.
- An antibiotic called rifampicin.
- Medicines known as prostaglandin synthetase inhibitors (e.g. ibuprofen, aspirin).
- Medicines known as sympathomimetic agents used for asthma (e.g. salbutamol), to stimulate your heart (e.g. isoprenaline) and in some cough and cold preparations.
- Medicines for treating diabetes (e.g. insulin or oral anti-diabetic medicines).
- Medicines that work by reducing the amount of important chemicals; adrenaline and catecholamines, that are involved in nerve function (e.g. reserpine).
If you are going to have surgery
If you are going to have an operation in hospital or going to the dentist, tell the doctor at the hospital or the dentist that you are taking Prestim Tablets.
Certain anaesthetics should not be used with these tablets (e.g. ether, cyclopropane, trichloroethylene). You should not be given a local anaesthetic combined with adrenaline while you are taking Prestim Tablets.
Taking Prestim Tablets with food and drink
You should avoid excessive alcohol consumption while taking Prestim.
Pregnancy and breast-feeding
Tell your doctor before you take any tablets if you are pregnant or breast-feeding. Also, tell your doctor if you become pregnant during treatment.
Do not take Prestim tablets if you are pregnant.
Your doctor will decide if you should take Prestim while you are breast-feeding.
Driving and using machines
This medicine may cause tiredness or dizziness as a side effect.
Therefore you should be careful if you are going to drive or operate machinery.
How To Take Prestim Tablets
Always take Prestim exactly as your doctor has told you.You should check with your doctor or pharmacist if you are not sure.
The usual dose can vary from 1 to 4 tablets.
You can take the tablets as a single dose in the morning or in two doses, one in the morning and the other in the evening.
Prestim Tablets should be swallowed whole with water.
If you take more Prestim Tablets than you should
If you or anyone else accidentally take more than the recommended dose of these tablets, call your doctor straight away or go to your nearest hospital casualty department.
If you forget to take Prestim
If you forget to take your tablet(s), take the next dose as normal.
Do not take a double dose to make up for forgotten tablet(s).
If you stop taking Prestim
Keep taking the Prestim Tablets for as long as your doctor tells you to. Do not stop taking them without consulting your doctor first. If it is right for you to stop taking Prestim then your doctor will probably reduce the dose gradually since it is important not to stop suddenly.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
Prestim Tablets Side Effects
Like all medicines, Prestim can cause side effects, although not everybody gets them.
Tell your doctor immediately if you experience severe abdominal pain and vomiting or you notice inflammation of your blood vessels (e.g. veins).
Tell your doctor if you notice a skin rash and/ or your eyes feel dry. Your doctor may decide to change your treatment. If you have a skin rash, this may be associated with an increased sensitivity to sunlight.
Tell your doctor if you have any of the side effects mentioned below and you are concerned:
- Upset stomach, dizziness, tiredness, depression, weakness, sleeplessness, breathing difficulties, a slow heart beat or other heart problems.
- You may also experience tired or painful muscles, feel thirsty and pass less urine than normal.
- If you are short sighted this may get worse.
Some side effects will not normally be noticed. These include an increase in blood sugar and sugar in the urine (particularly in people who are diabetic), changes in levels of some substances in the blood, such as decrease in potassium or an increase in urea, and changed blood cells. Your doctor may therefore need to do some tests.
Tell your doctor or pharmacist if you notice any side effects not listed in this leaflet, or if any of these effects become serious.
How To Store Prestim Tablets
Keep out of the reach and sight of children.
Store Prestim Tablets below 25°C.
Do not use Prestim after the expiry date which is stated on the bottle label and outer carton after the text “EXP“. The expiry date refers to the last day of that month.
Medicines must not be disposed of via wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer required.These measures will help to protect the environment.
Further Information
What Prestim contains
Active substance:
Timolol maleate and bendroflumethiazide. Each tablet contains 10 mg of timolol maleate and 2.5 mg
of bendroflumethiazide.
Other ingredients:
Microcrystalline cellulose, starch and magnesium stearate.
What Prestim looks like and contents of the pack
Prestim Tablets are white, flat and oval with “ ” imprinted on one side and a break-mark on the other.
Prestim comes in bottles of 30 tablets.
Marketing Authorisation Holder
Manufacturer
For any information about this medicine, please contact the Marketing Authorisation Holder.
This leaflet was last revised in July 2010.
34842E0EU-D00
562103V4130UK00
No comments:
Post a Comment